William Baier, MS, CSCS, USAW, CFL2
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September 12, 2025
What Is Ozempic?
Ozempic is the brand name for semaglutide, a type of medication called a GLP-1 receptor agonist. Originally developed to help manage type 2 diabetes, it works by mimicking a natural hormone in the body (GLP-1) that regulates blood sugar, slows digestion, and signals fullness to the brain. The result: people feel less hungry and tend to eat less without as much effort or willpower.
How Does It Work?
- Appetite control: GLP-1 medications help reduce cravings and increase feelings of fullness.
- Slowed digestion: Food moves through the stomach more slowly, which helps regulate blood sugar and prolongs satiety.
- Better blood sugar management: Especially helpful for those with insulin resistance or prediabetes.
Other Common Medications
Ozempic isn’t the only GLP-1 medication out there. Wegovy is another brand of semaglutide approved specifically for weight loss, while Mounjaro (tirzepatide) is a newer option that targets two hormones instead of one. All work in similar ways and are being studied closely for their effectiveness and safety.
The Pros
- Highly effective: Clinical trials show significant and sustained weight loss for many users.
- Health improvements: Reductions in blood sugar, blood pressure, and risk factors for heart disease.
- Quality of life: For people struggling with obesity-related issues, these medications can be a life-changing tool.
The Cons
- Side effects: Nausea, digestive discomfort, and in rare cases more serious complications.
- Cost and access: Not always covered by insurance, and often expensive.
- Temporary tool: If lifestyle changes aren’t made alongside medication, weight can return once the drug is stopped.
- Stigma and misuse: Some people attempt to obtain or use these drugs without a prescription, which is unsafe and strongly discouraged.
Fitness & Lifestyle: Where the Real Change Happens
While these medications can be an incredible lever for jumpstarting weight loss, they’re not magic. To keep results long-term, you still need the basics:
- Regular training to build lean muscle and support metabolism.
- Nutrition habits that are sustainable and enjoyable.
- Sleep and stress management to keep hormones and recovery on track.
- Identity shifts that turn “I’m on a diet” into “I’m a person who moves, eats well, and takes care of myself.”
With the right coaching, it’s possible to wean off medication completely and maintain results through lifestyle and fitness.
The Bottom Line
Ozempic and similar medications are powerful tools—especially for people who’ve struggled for years to lose weight. Used responsibly, under medical supervision, they can change lives. But lasting results still come from habit change, training, and coaching. Medications can give you momentum, but your lifestyle is the engine that keeps you moving forward.
